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An inverse association between the Mediterranean diet and bladder cancer risk: a pooled analysis of 13 cohort studies.

Author(s) : Witlox WJA., van Osch FHM., Brinkman M., Jochems S., Goossens ME., Weiderpass E., White E., Van Den Brandt PA., Giles GG., Milne RL., Huybrechts I., Adami HO., Bueno-de-Mesquita B., Wesselius A., Zeegers MP.
Date : Feb, 2019
Source(s) : European Journal Of Nutrition
Adresse : Department of Complex Genetics and Epidemiology, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University, Universiteitssingel 40, 6200 MD, Maastricht, The Netherlands.

PURPOSE
The role of diet in bladder carcinogenesis has yet to be established. To date most studies have investigated dietary components individually, rather than as dietary patterns, which may provide stronger evidence for any influence of diet on bladder carcinogenesis. The Mediterranean diet has been associated with many health benefits, but few studies have investigated its association with bladder cancer risk.

METHODS
We investigated the potential association between the Mediterranean diet score (MDS) and risk of developing bladder cancer by pooling 13 prospective cohort studies included in the BLadder cancer Epidemiology and Nutritional Determinants (BLEND) study and applying a Cox regression analysis.

RESULTS
Dietary data from 646,222 study participants, including 3639 incident bladder cancer cases, were analysed. We observed an inverse association between Mediterranean diet and bladder cancer risk (HR

CONCLUSION
We found evidence that adherence to the Mediterranean diet was associated with reduced risk of developing bladder cancer, suggesting a positive effect of the diet as a whole and not just one component.

Source : Pubmed

 

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