Anti-atherogenicity of nutritional antioxidants.

Auteur(s) :
Fuhrman B., Aviram M.
Date :
Jan, 2001
Source(s) :
IDRUGS. #4:1 p82-92
Adresse :
The Lipid Research Laboratory, Rambam Medical Center, Haifa, Israel, 31096.

Sommaire de l'article

Epidemiological studies have indicated that fruit- and vegetable-rich diets play a protective role against cardiovascular disease. An explanation for this protection lies in the presence of antioxidant vitamins in fruits and vegetables. A large number of studies have provided data suggesting that consumption of dietary antioxidants is associated with reduced risk for cardiovascular disease. Plausible mechanisms by which these antioxidants may reduce the development of atherosclerosis include inhibition of low-density lipoprotein (LDL) oxidation, cellular lipid peroxidation and cell-mediated oxidation of LDL, and reduction in blood cholesterol levels. This review reports on the recent data of the anti-atherosclerotic effects and mechanistical aspects of three major groups of dietary antioxidants: vitamin E, carotenoids and flavonoids.

Source : Pubmed