Comparative Studies on Polyphenolic Composition, Antioxidant and Antimicrobial Activities of Schisandra chinensis Leaves and Fruits.

Auteur(s) :
Mocan A., Crisan G., Vlase L., Crisan O., Vodnar DC., Raita O., Gheldiu AM., Toiu A., Oprean R., Tilea I.
Date :
Sep, 2014
Source(s) :
Molecules. #19:9 p15162-79
Adresse :
Department of Pharmaceutical Botany, Iuliu Hatieganu University of Medicine and Pharmacy, 12 I. Creanga Street, Cluj-Napoca 400010, Romania. [email protected] Department of Pharmaceutical Botany, Iuliu Hatieganu University of Medicine and Pharmacy, 12 I. Creanga Street, Cluj-Napoca 400010, Romania. [email protected] Department of Pharmaceutical Technology and Biopharmaceutics, Iuliu Hatieganu University of Medicine and Pharmacy, 12 I. Creanga Street, Cluj-Napoca 400010, Romania. [email protected] Department of Organic Chemistry, Iuliu Hatieganu University of Medicine and Pharmacy, 12 I. Creanga Street, Cluj- Napoca 400010, Romania. [email protected] Department of Food Science and Technology, University of Agricultural Sciences and Veterinary Medicine, 3-5 Manastur Street, Cluj-Napoca 400372, Romania. [email protected] Department of Physics of Nanostructured Materials, National Institute for Research and Development of Isotopic and Molecular Technologies 65-103, Donath Street, Cluj-Napoca 400010, Romania. [email protected] Department of Pharmaceutical Technology and Biopharmaceutics, Iuliu Hatieganu University of Medicine and Pharmacy, 12 I. Creanga Street, Cluj-Napoca 400010, Romania. [email protected] Department of Pharmacognosy, Iuliu Hatieganu University of Medicine and Pharmacy, 12 I. Creanga Street, Cluj-Napoca 400010, Romania. [email protected] Department of Analytical Chemistry and Instrumental Analysis, Iuliu Hatieganu University of Medicine and Pharmacy, 4 L. Pasteur Street, Cluj-Napoca 400010, Romania. [email protected] Family Medicine, Department M3 Clinical Sciences Internal Medicine, University of Medicine and Pharmacy, 38 G. Marinescu Street, Targu Mures 540139, Romania. [email protected]

Sommaire de l'article
Imprimer

The aim of this paper was to evaluate the antioxidant and antimicrobial activities and the polyphenolic content of Schisandra chinensis (Turcz.) Baill. leaves and fruits. The leaves are an important source of flavonoids (35.10 ± 1.23 mg RE/g plant material). Qualitative and quantitative analyses of the polyphenolic compounds were achieved using a HPLC-UV-MS method. The main flavonoid from the leaves was isoquercitrin (2486.18 ± 5.72 μg/g plant material), followed by quercitrin (1645.14 ± 2.12 μg/g plant material). Regarding the fruit composition, the dominant compound there was rutin (13.02 ± 0.21 μg/g plant material), but comparing with the leaves, fruits can be considered a poor source of phenolic compounds. The antioxidant activity was evaluated by DPPH, TEAC, hemoglobin ascorbate peroxidase activity inhibition (HAPX), inhibition of lipid peroxidation catalyzed by cytochrome c and EPR spectroscopic assays, revealing a better antioxidant activity for the S. chinensis leaves extract. In the antimicrobial assay, S. chinensis leaves extract showed efficient activities against the targeted bacteria, being more active than the fruits extract. The results suggest the leaves of S. chinensis as a valuable source of antioxidant compounds with significant antioxidant activity.

Source : Pubmed
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