Dietary Intake of Fiber, Fruit, and Vegetables Decrease the Risk of Incident Kidney Stones in Women: A Women’s Health Initiative (WHI) Report.

Auteur(s) :
Wactawski-wende J., Sorensen MD., Hsi RS., Achia T., Shara N., Kahn AJ., Wang YH., Hou L., Stoller ML., Writing Group .
Date :
Mai, 2014
Source(s) :
The Journal of urology. #: p
Adresse :
Division of Urology, Dept of Veteran Affairs Medical Center, and Dept of Urology, Urological Research Outcomes Collaboration (UROC), University of Washington School of Medicine, Seattle, WA. Electronic address: [email protected]

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PURPOSE
We evaluated the relationship between dietary fiber, fruit, and vegetable intake, and the risk of kidney stone formation.

METHODS
Overall, 83,922 postmenopausal women from the WHI Observational Study were included and followed prospectively. Cox proportional hazards regression analyses evaluated the associations between total dietary fiber, fruits, and vegetable intake, and the risk of incident kidney stone formation adjusting for nephrolithiasis risk factors (age, race/ethnicity, geographic region, diabetes mellitus, calcium supplementation, hormone therapy use, body mass index, calibrated caloric intake, and dietary water, sodium, animal protein, and calcium intake). Women with a prior history of kidney stones (3,471 women) were analyzed separately.

RESULTS
Mean age was 64±7 years, 85% of women were Caucasian and 2,937 women (3.5%) experienced a kidney stone occurrence in 8 years median follow-up. In women with no history of kidney stones, higher total dietary fiber (6-26% decreased risk, p<0.001), higher fruit intake (12-25% decreased risk, p<0.001), and higher vegetable intake (9-22% decreased risk, p=0.002) were associated with a decreased risk of incident kidney stone formation in separate adjusted models. In women with a history of stones, there were no significant protective effects of fiber, fruits, or vegetable intake on the risk of kidney stone recurrence.

CONCLUSIONS
Greater dietary intake of fiber, fruits and vegetables were each associated with a reduced risk of incident kidney stones in postmenopausal women. The protective effects were independent of other known risk factors for kidney stones. In contrast, there was no reduction in risk in women with a history of stones.

Source : Pubmed
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