Fruit and vegetable intake and the risk of cataract in women
Sommaire de l'article
Author(s): Christen WG, Liu SM, Schaumberg DA, Buring JE
Source: AMERICAN JOURNAL OF CLINICAL NUTRITION 81 (6): 1417-1422 JUN 2005
Document Type: Article
Abstract: Background: Prospective data on cataract in relation to total fruit and vegetable intake are limited.
Objective: We aimed to examine whether higher fruit and vegetable intake reduces the risk of cataract and cataract extraction in a large, prospective cohort of women.
Design: Fruit and vegetable intake was assessed at baseline in 1993 among 39 876 female health professionals with the use of a validated, semiquantitative food-frequency questionnaire. A total of 35 724 of these women were free of a diagnosis of cataract at baseline and were followed for incident cataract and cataract extraction. Cataract was defined as an incident, age-related lens opacity responsible for a reduction in best-corrected visual acuity to 20/30 or worse, based on self-report confirmed by medical record review. Individuals, rather than eyes, were the unit of analysis.
Results: During an average of 10 y of follow-up, 2067 cataracts and 1315 cataract extractions were confirmed. Compared with women in the lowest quintile of fruit and vegetable intake, women with higher intakes had modest 10-15% reduced risks of cataract (P for trend < 0.05). For cataract extraction, no significant inverse trend was observed (P for trend = 0.12).
Conclusion: These prospective data suggest that high intake of fruit and vegetables may have a modest protective effect on cataract.
Author Keywords: cataract; cataract extraction; fruit and vegetables; prospective cohort; Women's Health Study
KeyWords Plus: NUCLEAR LENS OPACITIES; CIGARETTE-SMOKING; NUTRIENT INTAKE; BETA-CAROTENE; RAT LENSES; VITAMIN-A; DIET; MEN; EYE; EXTRACTION
Addresses: Christen WG (reprint author), 900 Commonwealth Ave E, Boston, MA 02215 USA
Brigham & Womens Hosp, Dept Med, Div Prevent Med, Boston, MA 02115 USA
Harvard Univ, Sch Med, Dept Ambulatory Care & Prevent, Boston, MA 02115 USA
Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA
E-mail Addresses: email@example.com
Publisher: AMER SOC CLINICAL NUTRITION, 9650 ROCKVILLE PIKE, SUBSCRIPTIONS, RM L-3300, BETHESDA, MD 20814-3998 USA, http://www.faseb.org/ascn
Discipline: ENDOCRINOLOGY, METABOLISM & NUTRITION
ENDOCRINOLOGY, NUTRITION & METABOLISM