Low carbohydrate diet from plant or animal sources and mortality among myocardial infarction survivors.

Auteur(s) :
Willett WC., Rimm EB., Liu S., Hu FB., Rexrode KM., Flint A., Pai JK., Forman JP., Mukamal KJ.
Date :
Sep, 2014
Source(s) :
J Am Heart Assoc. #3:5 pe001169
Adresse :
Department of Epidemiology, Harvard School of Public Health, Boston, MA (S.L., A.F., F.B.H., W.C.W., E.B.R.). shl607@mail.harvard.edu

Sommaire de l'article

BACKGROUND
The healthiest dietary pattern for myocardial infarction (MI) survivors is not known. Specific long-term benefits of a low-carbohydrate diet (LCD) are unknown, whether from animal or vegetable sources. There is a need to examine the associations between post-MI adherence to an LCD and all-cause and cardiovascular mortality.

METHODS AND RESULTS
We included 2258 women from the Nurses' Health Study and 1840 men from the Health Professional Follow-Up Study who had survived a first MI during follow-up and provided a pre-MI and at least 1 post-MI food frequency questionnaire. Adherence to an LCD high in animal sources of protein and fat was associated with higher all-cause and cardiovascular mortality (hazard ratios of 1.33 [95% CI: 1.06 to 1.65] for all-cause mortality and 1.51 [95% CI: 1.09 to 2.07] for cardiovascular mortality comparing extreme quintiles). An increase in adherence to an animal-based LCD prospectively assessed from the pre- to post-MI period was associated with higher all-cause mortality and cardiovascular mortality (hazard ratios of 1.30 [95% CI: 1.03 to 1.65] for all-cause mortality and 1.53 [95% CI: 1.10 to 2.13] for cardiovascular mortality comparing extreme quintiles). An increase in adherence to a plant-based LCD was not associated with lower all-cause or cardiovascular mortality.

CONCLUSIONS
Greater adherence to an LCD high in animal sources of fat and protein was associated with higher all-cause and cardiovascular mortality post-MI. We did not find a health benefit from greater adherence to an LCD overall after MI.

Source : Pubmed
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