Probabilistic acute risk assessment of cumulative exposure to organophosphorus and carbamate pesticides from dietary vegetables and fruits in Shanghai populations.

Auteur(s) :
Li S., Chen B., Wu M., Liu F., Yuan Y., Meng P.
Date :
Jan, 2017
Source(s) :
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. # p
Adresse :
a Key Laboratory of Public Health Safety of Ministry of Education, Collaborative Innovation Center of Social Risks Governance in Health, School of Public Health, Fudan University , Shanghai , China.

Sommaire de l'article

Organophosphorus (OPs) and carbamate pesticides (CPs) are among the most widely used pesticides in China, playing a major role in protecting agricultural commodities. In this study, we determined the cumulative acute exposure to organophosphate and carbamate pesticides of Shanghai residents from vegetables and fruits (VFs). The food consumption data were obtained from the Shanghai Food Consumption Survey (SHFCS) of 2012-2014 including a total of 1973 participants aged 2-90 years. The pesticide residue data were obtained from the Shanghai monitoring program during 2008-2011 with 34 organophosphates and 11 carbamates analyzed in a total of 5335 samples of VFs. A probabilistic approach was performed as recommended by the EFSA, using the optimistic model with non-detects set as zero and with processing factors (PFs) being used and the pessimistic model with non-detects replaced by limit of detection (LOD) and without PFs. We used the relative potency factor (RPF) method to normalize the various pesticides to the index compound (IC) of methamidophos and chlorpyrifos separately. Only in the pessimistic model using methamidophos as the IC, there was small risk of exposure exceeding the ARfD (3 µg kg(-1) bw day(-1)) in the populations of preschool children (0.029%), school-age children (0.022%), and adults (0.002%). There were no risk of exposure exceeding the ARfD of methamidophos in the optimistic model and of chlorpyrifos (100 µg kg(-1) bw day(-1)) in both optimistic and pessimistic models in all three populations. Considering the Chinese habits of overwhelmingly eating processed food (vegetables being cooked and fruits being washed or peeled), we conclude that little acute risk was found for the exposure to VFs sourced organophosphorus and carbamate pesticides in Shanghai.

Source : Pubmed