Rising prostate cancer rates in south korea

Auteur(s) :
Blair AM., Chokkalingam AP., Hsing AW., Lee DH., Kang D., Park SK., Sakoda LC., Kleef EV., Shin HR., Shin MH., Lee CW., Devesa SS., Ahn YO.
Date :
Sep, 2006
Source(s) :
PROSTATE. #66:12 p1285-1291
Adresse :
Addresses: Park SK (reprint author), Seoul Natl Univ, Coll Med, Dept Prevent Med, 28 Yeongeon Dong, Seoul 110799, South Korea Seoul Natl Univ, Coll Med, Dept Prevent Med, Seoul 110799, South Korea NCI, Div Canc Epidemiol & Genet, NIH, Rockville, MD USA Seoul Natl Univ, Coll Med, Dept Prevent Med, Seoul, South Korea Univ Calif Berkeley, Sch Publ Hlth, Div Epidemiol, Berkeley, CA USA Seoul Natl Univ, Coll Med, Dept Urol, Seoul, South Korea Korea Natl Canc Ctr, Res Inst Natl Canc Control & Evaluat, Goyang, South Korea Sungkyunkwan Univ, Sch Med, Dept Social & Prevent Med, Suwon, South Korea Keimyung Univ, Sch Med, Dept Prevent Med, Taegu, South Korea Kyungpook Univ, Coll Med, Dept Prevent Med, Taegu, South Korea E-mail Addresses: [email protected] Publisher: WILEY-LISS, DIV JOHN WILEY & SONS INC, 111 RIVER ST, HOBOKEN, NJ 07030 USA, http://www.wiley.com Discipline: UROLOGY & NEPHROLOGY MEDICAL RESEARCH, ORGANS & SYSTEMS CC Editions/Collections: Clinical Medicine (CM); Life Sciences (LS)

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BACKGROUND. Prostate cancer incidence and mortality rates in South Korea are relatively low, but rising steadily.
METHODS. We examined age-standardized incidence and mortality trends of prostate cancer in South Korea to gain further insight into prostate cancer etiology.
RESULTS. Although prostate cancer incidence has been low (7.9 per 100,000 man-years), it has increased up to 28.2% between 1996-1998 and 1999-2001. Prostate cancer mortality increased 12.7-fold over a 20-year period. Despite the increase in prostate cancer incidence and mortality rates, marked differences in rates remain for Koreans, Korean Americans, and Caucasian Americans.

CONCLUSIONS. The rising rates of prostate cancer in South Korea cannot be attributed entirely to PSA screening due to the low PSA screening prevalence; this trend is most likely related to increased westernization among Koreans. Interdisciplinary epidemiological studies incorporating the collection of biological samples are needed to clarify the extent to which lifestyle and genetic factors contribute to the observed racial disparity.

Source : Pubmed
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