Weight outcome after 2 years of a diet that excludes six processed foods: exploratory study of the « 1,2,3 diet » in a moderately obese population.

Auteur(s) :
Courie R., Gaillard M., Lainas P., Hansel B., Naveau S., Dagher I., Tranchart H.
Date :
Juil, 2018
Source(s) :
Diabetes, metabolic syndrome and obesity : targets and therapy. #11 p345-355
Adresse :
Department of Hepato-Gastroenterology and Nutrition, Antoine Béclère Hospital (AP-HP), Clamart, France, [email protected].

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Background
The Paleolithic diet, a diet devoid of food-processing procedure, seems to produce a greater decrease in weight compared to healthy reference diets but its limited food choices make it difficult to implement in our modern times where refined food is dominant.

Objective
To evaluate the effects of a 2-year diet that excludes only six refined foodstuffs implicated in obesity. Professional contact was kept minimal to approximate the approach used by most dieters.

Design
Single-arm, open-label, exploratory study.

Setting
One academic medical center, outpatient setting.

Patients
One hundred and five subjects with a mean age of 50 (SD, 14 years) and mean body mass index of 30.5 kg/m

Intervention
An ad libitum diet that excludes six refined foodstuffs (margarine, vegetable oils, butter, cream, processed meat, and sugary drinks) called the "1,2,3 diet".

Outcomes
Weight at 2 years was the primary outcome. Secondary outcomes included number of patients who lost more than 5% of initial body weight, glycated hemoglobin (HbA

Results
Average weight loss was 4.8 kg (

Conclusion
In this exploratory study, there was a significant long-term weight loss with the "1,2,3 diet" despite minimal professional contact. Given the lack of a control group and high attrition rate, further evaluation of this diet is warranted.

Source : Pubmed
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